All articles in IJMS (ISSN 1422-0067) Vol 24, Issue 5, are now freely available to access, read and download: https://fal.cn/3xpOY COVER STORY: Skin cancer is a prevalent form of cancer, particularly among Caucasian populations. The condition typically originates from cells in the epidermal layer of the skin, which are often oxygen-deprived. The three primary forms of skin cancer are malignant melanoma, basal cell carcinoma, and squamous cell carcinoma. Research has shown that hypoxia plays a cr
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Researchers from Florida Atlantic University investigated the underlying effects of amphetamine on embryogenesis for the first time. The study, published in the open access International Journal of Molecular Sciences (IJMS) uses a tiny worm, C. elegans, to investigate the effect of amphetamines on the embryo. The results from this study demonstrate that high levels of amphetamines during embryogenesis cause epigenetic effects on key dopamine transporter proteins. In addition, the researchers est
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Researchers from Dublin, Ireland developed a new gene therapy to improve mitochondrial function in glaucoma patients. In the study published in the Open Access journal International Journal of Molecular Sciences (IJMS) the researchers enhanced the NDI1 gene. They delivered it to three models: two variations of animal models, and human cells derived from glaucoma patients. The researchers aimed to improve mitochondrial function as well as, to decrease the amount of reactive oxidative species (ROS
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