The Steelers finished second in the AFC North in 2024, meaning they will play a second-place schedule in the 2025 season. That gave them the draw of the Seattle Seahawks, Indianapolis Colts, and Los Angeles Chargers for the open holes on their schedule as unique opponents compared to the rest of the AFC North.

The Pittsburgh Steelers made a shocking trade after the draft, dealing away their top receiver to the Dallas Cowboys. The Steelers shipped away George Pickens, who just turned 24 and is still on his rookie contract, after leading the team in receiving yards in each of the last two seasons.