Understanding human gene function in living organisms has long been hampered by fundamental differences between species.

Scientists first read the human genome, a three-billion-letter biological book, in April 2003. Since then, researchers have steadily advanced the ability to write DNA, moving far beyond single-gene ...

Understanding human gene function in living organisms has long been hampered by fundamental differences between species. Although mice share most ...

This important study, which tackles the challenge of analyzing genome integrity and instability in unicellular pathogens by introducing a novel single-cell genomics approach, presents compelling ...

Genetic disorders occur due to alterations in the primary genetic material, deoxyribonucleic acid (DNA), of an organism.

Therapeutic Potential of CRISPR–Cas3 Genome-Editing System for Transthyretin Amyloidosis. Credit: Institute of Medical ...

CRISPR–Cas9-based therapies are widely investigated for their clinical applications. However, there are limitations ...

SNPBag is a large language model pre-trained with whole-genome SNP data from 1 million synthetic individuals. It is currently fine-tuned for 5 tasks: Folders contain code for reproducing figures on ...

He Jiankui spent three years in prison after creating gene-edited babies. Now back at work, he sees a greater opening for ...

A stretch of viral DNA in the mouse genome gives cells in early-stage embryos the potential to become almost any cell type in ...

Trained on 9.7 trillion tokens of evolutionary data, EDEN designs therapeutics from large gene insertion to antimicrobial peptides.