"Our results indicate that the bacteria's CRISPR system was more effective at using the naturally dormant phage to pull parts of the viral genetic code into their genome," says Modell.

Like people, bacteria get invaded by viruses. In bacteria, the viral invaders are called bacteriophages, derived from the ...

CRISPR is a double-edged sword. It evolved to help bacteria slay phages. But CRISPR components can also be engineered into phages, arming them against bacteria. Consequently, phage therapy says ...

Model of CRISPR, phage co-evolution explains confusing experimental results. Your friend's email. Your email. I would like to subscribe to Science X Newsletter. Learn more. Your name. Note.

In this way, the researchers reported in 2016 in mBio, CRISPRs are “one of the fundamental drivers of phage evolution.” CRISPR systems can be picked up, dropped, then picked up again by ...

The phage-fighting potency of CRISPR-Cas13 was unexpected given how few microbes use it, explained Adler. The scientists were doubly surprised because the phages it defeated in testing all infect ...

CRISPR, the Nobel Prize-winning gene editing technology, ... The phage-fighting potency of CRISPR-Cas13 was unexpected given how few microbes use it, explained Adler.

The inhibitory RNAs named "Racrs" are a significant breakthrough in efforts to control CRISPR-Cas technologies and improve phage therapy, an alternative to antibiotics.

CRISPR-Cas9 has long been likened to a kind of genetic ... "Cas10 alone can clear a phage or plasmid from a cell as long as ...

As with CRISPR-less phage therapies, clinical trials are needed to determine the treatment's safety profile and appropriate dosing. "I can see these [treatments] coming about in the five- to 10 ...

As with CRISPR-less phage therapies, clinical trials are needed to determine the treatment's safety profile and appropriate dosing. "I can see these [treatments] coming about in the five- to 10 ...

“The Crispr-enhanced phages allow for degradation of the bacterial genome and would bypass several mechanisms by which bacteria can become resistant to phage,” says Saima Aslam, a professor of ...