MLB Trade Deadline 2025: Instant Takeaways to Padres Landing Mason Miller originally appeared on Athlon Sports. The surging San Diego Padres entered the 2025 MLB trade deadline with three All-Star relievers already in their bullpen. They now have a fourth.

After making some of the biggest splashes of the MLB trade deadline, the San Diego Padres and Seattle Mariners emerged as the biggest odds movers and most popular selections for bettors in the futures markets.

The St. Louis Cardinals (55-55) visit the San Diego Padres (60-49) open a 3-game series Friday at Petco Park. First pitch is scheduled for 9:40 p.m. ET. Let's analyze BetMGM Sportsbook's MLB odds around the Cardinals vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Preview the Aug. 3 matchup between the San Diego Padres and St. Louis Cardinals with odds over/under, game spread, betting lines and more.

The Los Angeles Dodgers go on the road to play against the Tampa Bay Rays in the second game of their series on Saturday. Los Angeles has won three of its last four games, including a 5-0 shutout win over Tampa Bay last night.