Genetic repair via CRISPR can inadvertently introduce other defects, researchers show
The CRISPR molecular scissors have the potential to revolutionize the treatment of genetic diseases. This is because they can ...
RNA-targeting CRISPR reveals that hundreds of noncoding RNAs are essential—not 'junk'
Genes contain instructions for making proteins, and a central dogma of biology is that this information flows from DNA to RNA ...
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Use of 'genetic scissors' carries risks
The CRISPR tool is capable of repairing the genetic defect responsible for the immune disease chronic granulomatous disease. However, researchers have now shown that there is a risk of inadvertently ...
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A new chemistry for CRISPR
"It's a completely brand-new type of CRISPR chemistry," says co-first author Christian Baca, a TPCB graduate student in the Marraffini lab. "It's more evidence that CRISPR systems have an array of ...
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CRISPR Systems Have More Than One Strategy in Their Toolkit
Researchers discovered that the CRISPR-Cas10 system not only cuts viral DNA but also produces toxic cyclic-oligoadenylates ...
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Gene editing with CRISPR may introduce new defects
The CRISPR tool is capable of repairing the genetic defect responsible for the immune disease chronic granulomatous disease.
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Gene Repair via CRISPR May Trigger Unwanted Defects
The research team has now succeeded in using the CRISPR system to insert the missing letters in the right place. They ...
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CRISPR and Gene Editing: How Boston is Leading in Biotech
Boston has become one of the top places for biotech research, and one of the big players in this space is CRISPR gene-editing ...