Ewing sarcoma (ES) and its variants are rare and aggressive malignancies, occurring in paediatric and younger adult populations. Adamantinoma-like ES (ALES) is one of its variants, characterised by ...

We present a case of human epidermal growth factor receptor 2 (HER2)-overexpressing, alpha-fetoprotein (AFP)-producing metastatic gastric adenocarcinoma diagnosed in the USA. Both HER2 overexpression ...

Cervical spine clearance in trauma patients is frequently guided by strict protocols, particularly when patients present with midline cervical tenderness or cannot be reliably examined. Although a ...

Abdominal aortic aneurysm (AAA) is an extremely rare condition in paediatric patients but can occur more frequently in patients with congenital connective tissue diseases such as Marfan syndrome or ...

Headaches in pregnancy are a common occurrence, and most differentials are benign but cerebral venous thrombosis (CVT) is a life-threatening secondary headache that is more common in pregnancy and ...

A male in his 50s presented with profound leucocytosis, systemic symptoms and marked hepatosplenomegaly. Initial workup with peripheral blood flow cytometry suggested T-cell prolymphocytic leukaemia ...

This report documents a young female patient with microgranular variant acute promyelocytic leukaemia (APL) harbouring FLT3-ITD mutation who presented with fatigue, fever, gum bleeding and altered ...

This case report details an ST-segment elevation due to ileus and gastric dilation. The ECG recorded in a man in his 70s with nausea, vomiting and epigastric discomfort showed ST-segment elevation in ...

A female patient in her 60s with bipolar disorder type 1 underwent robot-assisted radical cystectomy with ileal conduit for muscle-invasive bladder cancer. Postoperatively, she continued her regular ...

Haemophagocytic lymphohistiocytosis (HLH) is a rare condition of uncontrolled immune activation as a result of an inherited genetic defect or in response to malignancy, autoimmune disease, ...

A man in his 70s presented to hospital with an acute kidney injury. He recently had started taking valacyclovir for treatment of shingles. The valacyclovir was stopped and his acute kidney injury ...

Aortic dissection is an uncommon diagnosis that typically presents with acute onset of severe pain. It rarely presents with minimal to no symptoms, which carries a higher mortality risk given the ...