Despite emerging clinical successes, current genome editors suffer from off-target effects and can trigger unwanted responses from the immune system, limiting their broader therapeutic applications.

The gene editing tool known as CRISPR-Cas9 is changing what's possible for treating a wide range of diseases caused by ...

Stanford researchers and their collaborators have revealed a new device that could change the way scientists conduct gene-editing experiments. The device, CRISPR-GPT, is an artificial intelligence lab ...

This study presents a comprehensive benchmarking of human-derived transcription activation domains (hTADs) for use in CRISPR-based artificial ...

A groundbreaking new study reveals a gene-editing therapy that dramatically lowered 'bad' cholesterol in monkeys, offering ...

A major medical milestone took place in May 2025, when doctors at the Children’s Hospital of Philadelphia used CRISPR-based gene editing to treat a child with a rare genetic disorder. Unlike earlier ...

Megan Molteni reports on discoveries from the frontiers of genomic medicine, neuroscience, and reproductive tech. She joined STAT in 2021 after covering health and science at WIRED. You can reach ...

Although existing CRISPR-Cas-based imaging methods can target endogenous genomic sequences, their applications are limited by system complexity and sensitivity, particularly when imaging ...

In a 15-patient, Phase 1, first-in-human trial, a one-time CRISPR-Cas9 gene-editing therapy safely reduced LDL cholesterol and triglycerides in people with difficult-to-treat lipid disorders, ...

And now a type of illness-resistant pig could soon join their ranks. British company Genus used the popular gene-editing technique CRISPR to make pigs immune to a virus that causes an illness called ...

The Influenza A virus (IAV) has been the cause of six major flu pandemics, responsible for 50 to 100 million deaths globally. In the U.S. alone, it is estimated that, despite seasonally updated ...