Understanding human gene function in living organisms has long been hampered by fundamental differences between species.

The National Academies of Sciences, Engineering, and Medicine are private, nonprofit institutions that provide expert advice on some of the most pressing challenges facing the nation and world. Our ...

This will be a conference call of the international commission developing a framework for considering technical, scientific, medical, regulatory, and ethical requirements for germline genome editing ( ...

CRISPR–Cas9-based therapies are widely investigated for their clinical applications. However, there are limitations ...

An international group of scientists is calling for a moratorium on making inheritable changes to the human genome, specifically the use of the Crisper-Cas9 technique on DNA. The group met in ...

Scientists first read the human genome, a three-billion-letter biological book, in April 2003. Since then, researchers have steadily advanced the ability to write DNA, moving far beyond single-gene ...

Understanding human gene function in living organisms has long been hampered by fundamental differences between species. Although mice share most ...

Scientists at the McGovern Institute and the Broad Institute of MIT and Harvard have reengineered a compact RNA-guided enzyme they found in bacteria into an efficient, programmable editor of human DNA ...

The promise of genome editing to help understand human diseases and create new therapies is vast, but technological limitations have limited advancement of the field. While existing editing ...

Waking up this morning to news of the much-deserved Nobel Prize win for Emmanuelle Charpentier and Jennifer A. Doudna "for the development of a method for genome editing" confirms the importance of ...