Narcolepsy with cataplexy, now known as type 1 narcolepsy, is a chronic neurological disorder that affects a person’s sleep-wake cycle and involves muscle weakness. The condition can cause a person to ...

Oveporexton significantly improves wakefulness and reduces cataplexy frequency in patients with narcolepsy type 1, according ...

Pitolisant is now the only treatment option not scheduled as a controlled substance that is indicated for both excessive daytime sleepiness and cataplexy in pediatric and adult patients. The Food and ...

Cataplexy, or sudden muscle weakness that can resemble fainting, may be prompted by strong emotions. This symptom isn't serious and mostly occurs with narcolepsy type one — otherwise, it's very rare.

Could you provide an overview of the Develop hypersomnia Understanding by Evaluating low-sodium oxybate Treatment (DUET) ...

Cataplexy is a sudden episode of muscle weakness that occurs while fully aware and conscious. It can be triggered by emotional events, such as laughing, crying or fear, and is usually transient in ...

Pitolisant (Wakix) in children ages 6 years and up led to clinically meaningful improvements in narcolepsy symptoms in a phase III trial. Among 110 kids with narcolepsy with or without cataplexy, ...

This week, the FDA approved Jazz Pharmaceuticals’ XywavTM (calcium, magnesium, potassium, and sodium oxybates), an oral solution for the treatment of cataplexy or excessive daytime sleepiness in ...

Aaron Schokman was in his second year of university when his life took a dramatic turn for the worse. No matter what he tried, he just couldn't stay awake. Loading... He would zone out during lectures ...

Orexins are neurotransmitters, which are chemicals in your brain that send messages from one neuron (a nerve cell) to another. When you’re awake, those neurons send out orexins. The orexins then bind ...

And not figuratively, either. Sometimes people have found that certain emotions literally cause their muscles to unhook from their brains. They collapse entirely. This is not some strange disease, or ...