UC Santa Cruz researchers have discovered a peptide in human RNA that regulates inflammation and may provide a new path for treating diseases such as arthritis and lupus. The team used a screening ...

A team from University of Toronto Engineering is the first to synthesize long noncoding RNA (lncRNA) outside the cell—a new ...

A research collaboration based in Kumamoto University (Japan) has identified a novel lncRNA, Caren, that is abundantly expressed in cardiomyocytes. They showed that it enhances energy production by ...

A newly revealed role of lncRNAs in the deadly malaria parasite, Plasmodium falciparum, has opened new avenues for targeted therapeutic strategies. Malaria continues to be one of the most critical ...

Sometimes highly impactful serendipitous discoveries are made when performing genetic loss-of-function studies that were initially focused on putative tumor suppressors or other hypotheses.

An Immune-metabolic signature (IMMETCOLS) identifies three clusters in mCRC with different immune-phenotype distribution and potential clinical implications. Deep neural networks and association with ...

Scientists have discovered evolutionarily conserved trans-lncRNA pairs that boost disease resistance in tea plants. These pairs, including the 12-oxophytodienoate reductase gene, interact with the ...

Patients with overproduction of protein from the chromodomain helicase DNA binding (CHD2) gene can develop a very rare and severe neurodevelopmental disorder with profound implications for their ...

To understand the human genome, scientists focused on protein-coding genes and their functions for decades. This has given us ...