The potential effects of astrocyte dysfunction in neurodegenerative diseases are summarized in Figure 2. AD is characterized clinically by cognitive loss in two or more domains, including memory, ...

Scientists have engineered a nanowire platform that mimics brain tissue to study astrocytes, the star-shaped cells critical for brain health, for the first time in their natural state. Astrocytes are ...

Once thought to play a supporting function in the brain, new research shows non-neuronal astroglial cells perform a leading role in regulating the activity of neurons and their connections. In 2019, ...

Why are we able to recall only some of our past experiences? A new study led by Jun Nagai at the RIKEN Center for Brain Science in Japan has an answer. Surprisingly, it turns out that the brain cells ...

A research team has identified different subtypes of white matter (WM) astrocytes, including a unique type with the ability to multiply and potentially aid in brain repair. Using single-cell RNA ...

How do astrocytes react to Alzheimer’s disease pathology? It’s complicated, according to the largest single-nuclei RNA-Seq study of these cells published thus far. Scientists led by Sudeshna Das at ...