A ribosome is composed of two subunits: large and small. During translation, ribosomal subunits assemble together like a sandwich on the strand of mRNA, where they proceed to attract tRNA molecules ...

During translation, multiple ribosomes travel along the nucleic acid chain to build polypeptides that become functional proteins. Occasionally, these molecular decoders pause on the mRNA, either ...

These spots are socRNAs being translated by ribosomes in a cell. They get brighter over time, showing active translation. The complex, which includes the socRNA and ribosome, is attached to the plasma ...

Internal ribosome entry sites (IRESs) are highly structured RNA elements that permit the recruitment of ribosomes for translation initiation independent of the conventional 5′-cap mechanism. Viruses ...

Slower ribosomes stall during translation and collide with faster ones, triggering selective degradation of their small subunits. This “ribosome competition” mechanism ensures that only efficient ...

Protein production (translation) is a complex process involving machinery called ribosomes. How do cells counter ribosomal destabilization leading to premature termination of translation? Scientists ...

The cells in living organisms are constantly making proteins. Ribosomes, the RNA-protein complexes that make other proteins, ...

ReAberrant translation initiation at non-AUG start codons is associated with cancer and neurodegenerative diseases. Therefore, identifying how non-AUG translation is regulated differently from ...

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a beta-CoV that recently emerged as a human pathogen and is the causative agent of the COVID-19 pandemic. A molecular framework of how ...