Cells have evolved careful checks to ensure DNA is copied only once, but how they switch on replication at the right moment ...

The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...

DNA replication is the process by which a cell makes an identical copy of its DNA. This process is performed at the beginning of every cell division so that when the cell divides, each daughter cell ...

Researchers have identified an alternate method to study changes during the DNA replication process in lab settings using genetically modified yeast. The new approach offers a clearer window than ...

The Polymerase Chain Reaction (PCR) is a technique for the amplification of DNA in vitro (this describes experiments with cells outside their normal environment). PCR amplifies DNA using complementary ...

Fig. 4: The process of establishment of pre-RCs at an S. cerevisiae origin in which the B2 domain is separated from the A and B1 origin elements. This Review focuses on the first step in eukaryotic ...

Scientists have discovered that a protein once thought to simply help load a factor necessary for the copying of DNA, actually plays a key role in ensuring fast and reliable replication—an insight ...

Before each cell division, eukaryotic cells must replicate their chromosomes to ensure the accurate transmission of genetic information. Chromosome replication involves more than just DNA duplication; ...

An elegant collaboration between researchers in the UK's two core-funded Medical Research Council Research Institutes, the Laboratory of Medical Sciences (LMS) in London and the Laboratory of ...