A previously unidentified physically activated pathway for cellular uptake in the body’s immune defence system could predate commonly recognized receptor-mediated processes. The pathway relies on ...

Magnetic beads pre-coupled with biotinylated proteins are ideal for highly efficient immunocapture, biopanning and virus capture with the help of a magnetic field. In addition to these common ...

Suppressing CD33 stimulates phagocytosis, slows plaque growth. A protective CD33 mutation could be a gain of function that activates phagocytosis. The CD33 receptor acts as a dimer. At the 14th ...

Far from a static barrier, the brain’s extensive interface with the blood is increasingly being appreciated as an active border, one that serves not only to keep some proteins out, but to let others ...

YF550-C1, an E3 ligase inhibitor of CBL-B, to demonstrate T cell and NK cell activation and anti-tumor activities in syngeneic and PDX tumor model. This is an ASCO Meeting Abstract from the 2024 ASCO ...

As microbes invade the human body, phagocytic cells such as macrophages spring into action to clear the intruders. These cells extend arm-like projections and wrap them around the microbes before ...

The coronavirus disease 2019 (COVID-19), which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused over 4.9 million deaths worldwide, as well as a significant ...

IBEC’s Principal Investigator César Rodriguez-Emmenegger has been awarded an ERC Consolidator Grant to develop Phagocytic Synthetic Cells (PSCs) to fight antibiotic-resistant pathogens. César ...

Phagocytosis can be viewed as a primitive immune system used by all cells. When a pathogen is near the cell, the cell membrane will deform to engulf the pathogen and dispose of it. Researchers have ...