In the Alzheimer’s disease brain, synaptic loss correlates with cognitive decline, and is considered a sign of disease progression. But is synaptic loss always bad? Provocative new data from several ...

Analysis of human brain tissue revealed differences in how immune cells behave in brains with Alzheimer's disease compared to healthy brains, indicating a potential new treatment target. University of ...

A study by Dorothy P. Schafer, PhD, and Travis E. Faust, PhD, at UMass Chan Medical School, explains how two different cell types in the brain—astrocytes and microglia—communicate in response to ...

A new study finds that microglia with mutant TREM2 protein reduce brain circuit connections, promote inflammation and contribute to Alzheimer's pathology in other ways. A rare but potent genetic ...

BOSTON, Mass. (July 15, 2024)—A groundbreaking study conducted at the lab of Beth Stevens, PhD, at Boston Children’s Hospital has revealed that an immune protein impacts neuronal protein synthesis in ...

A study in mice suggests infantile amnesia is not a failure of memory, but a developmentally useful process guided by brain ...

Scientists have revealed that immune cells in Alzheimer's brains behave differently from those in brains of people without the disease – a discovery that could lead to new treatments. Published in ...