Please provide your email address to receive an email when new articles are posted on . Mirum Pharmaceuticals received first treatment approval for treatment of cerebrotendinous xanthomatosis. Ctexli ...

Lipid metabolism and storage mechanisms underpin essential cellular processes, ensuring energy homeostasis and membrane integrity. At the cellular level, lipids are synthesised and stored ...

Scientists have identified a protein that acts as a kind of traffic controller for fat inside cells, revealing a mechanism that could help explain how the body regulates energy storage and why things ...

The FDA on Friday approved chenodiol (Ctexli) for the treatment of cerebrotendinous xanthomatosis (CTX) in adults. Chenodiol -- a naturally occurring human bile acid also known as chenodeoxycholic ...

Chanarin-Dorfman syndrome (CDS) is a rare autosomal recessive disorder manifesting predominantly as congenital ichthyosiform erythroderma and systemic accumulation of neutral lipids. Mutations in the ...

Chanarin-Dorfman syndrome (CDS) is a rare, multisystemic, neutral lipid storage disease (NLSD) where the triglyceride accumulates in the leukocytes and other organs. Image Credit: ...

In an effort five years in the making, researchers describe the interplay between fats and proteins in brain cells and how their dysfunction contributes to the development of late-onset Alzheimer's ...

CKD patients face higher CVD risk, with dyslipidemia differing from the general population, necessitating tailored lipid ...

The Food and Drug Administration approved Mirum Pharmaceuticals' Ctexli to treat Cerebrotendinous Xanthoma, a very rare lipid-storage disease. The approval makes Ctexli, or chenodiol, the first ...

AD is associated with significant changes in genes related to neuroinflammation, and lipids are crucial in this metabolic dysregulation. Abnormal phospholipid accumulation in the brain not only ...

The fact that having high cholesterol can cause health problems is well known. But a total cholesterol level that fluctuates a lot — either up or down within a five-year period — might also be ...