Although the genetic cause of many diseases have been identified, it's estimated that as many as 70% of patients with a rare ...
Many childhood cancers start with a hijacking at the molecular level. A group of abnormal proteins known as fusion proteins aberrantly engage with a collection of proteins that switches genes on and ...
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Multiple protein forms from a single gene offer fresh insight into rare disease mechanisms
Iain Cheeseman and colleagues reveal the underappreciated role of single genes producing multiple proteins in atypical ...
Despite the best efforts of modern medicine, Huntington’s disease is a condition that still comes with a tragic prognosis.
Researchers have mapped the regulatory elements that control the FOXP3 gene, which is implicated in maintaining balance in ...
The real revolution came in 2012, when researchers Jennifer Doudna and Emmanuelle Charpentier harnessed CRISPR, a natural bacterial defense system. In bacteria, CRISPR cuts out invading viruses’ DNA ...
Researchers at the University of Kansas have discovered a human gene, the protein PARP14, plays a role in regulating ...
In a world-first trial, scientists used a one-off CRISPR gene edit to switch off a liver “fat brake” gene, slashing stubborn ...
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Aquaporin gene duplication followed by mutation in European eels restores broad solute permeability
Common ancestor eels lost the aquaporin gene encoding proteins with broad solute permeability. Researchers from the Institute ...
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