For successful cell division, chromosomal DNA needs to be packed into compact rod-shaped structures. Defects in this process can lead to cell death or diseases like cancer. A new study has shown how ...
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How chromosomes shape up for cell division: Scientists reveal DNA loop formation mechanisms
Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves. For this, the cell must duplicate its DNA—its genome—and segregate it equally ...
Scientists have uncovered an unexpected function for a crucial protein involved in cell division. Reported in two consecutive ...
Scientists at Children's Medical Research Institute (CMRI) have made a major discovery about cancer cells. This new ...
New findings shed light on how chromosomes manage the various pushing and pulling forces generated when cells divide. Specifically, researchers show that chromosomes resist being punctured by the ...
Small, cancer-associated DNA circles "hitchhike" on chromosomes during cell division to spread efficiently to daughter cells by co-opting a process used to maintain cellular identity through ...
When we talk about memories in biology, we tend to focus on the brain and the storage of information in neurons. But there are lots of other memories that persist within our cells. Cells remember ...
The story of the cell cycle is often told only through the perspective of the chromosomes as they replicate and then divide. This resource beautifully illustrates the role of the cytoskeleton in that ...
Researchers have discovered key mechanisms and structural details of a fundamental biological process -- how a cell nucleus and its chromosomal material reorganizes itself after cell division. The new ...
Japanese researchers report a new ion detector, MARIO. Using it, they show that changes in the intracellular concentration of free magnesium ions (Mg 2+) is critical for the chromosome folding that ...
As the cell proceeds through the stages of cell division (from left to right: interphase, prometaphase, metaphase, and anaphase), chromosomes become progressively more compact through a combination of ...
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