The cerebellum is instrumental in coordinating movement and refining motor control through intricate neuronal circuitry, with Purkinje cells serving as the central integrators of sensory inputs and ...

Purkinje cell drawing by Santiago Ramón y Cajal circa 1899. Scientists at the annual 2014 Society for Neuroscience meeting (November 14-19) in Washington D.C. presented unpublished research that links ...

Although the prevailing wisdom among neuroscientists is that Purkinje cells have just one primary dendrite that connects with a single climbing fiber from the brain stem, new research shows that ...

Tracking the gene-expression profiles of individual cerebellar cells during development in humans, mice and opossums revealed evolutionarily conserved as well as species-specific cellular and ...

Scientists have developed a novel human brain organoid model that generates all the major cell types of the cerebellum, a hindbrain region predominantly made up of two cell types necessary for ...

Cerebellar granule cells (GrCs) are usually regarded as a uniform cell type that collectively expands the coding space of the cerebellum by integrating diverse combinations of mossy fiber inputs.

The evolution of higher cognitive functions in human beings has so far mostly been linked to the expansion of the neocortex – a region of the brain that is responsible, inter alia, for conscious ...

The Curious Marmoset. Here, Charlie stares at his reflection, wondering: “Hmmm, how does my tongue work?”. Photographed by Mohammad Amin Fakharian, Shadmehr Laboratory, Johns Hopkins University.

In 1906, Spanish scientist Santiago Ramón y Cajal won the Nobel Prize for his pioneering studies of the microscopic structures of the brain. His famous drawings of Purkinje cells in the cerebellum ...

In a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato has pioneered a novel human brain organoid model that generates all the major cell types of the cerebellum, a hindbrain ...