The process of energy generation by mitochondria is closely tied to intracellular calcium regulation by a membrane gateway inside mitochondria known as the mitochondrial Ca2+ uniporter (MCU). How MCU ...

The transport activity of human mitochondrial aspartate/glutamate carriers is central to the malate–aspartate shuttle, urea cycle, gluconeogenesis and myelin synthesis. They have a unique three-domain ...

Rab GTPases play key roles in the delivery, docking and fusion of intracellular vesicles. However, the mechanism by which spatial and temporal regulation of Rab GTPase activity is controlled is poorly ...

Milk has some competition when it comes to calcium.

You've heard that calcium protects your bones and that your glass of milk is loaded with it, but what do you really know about this essential nutrient? Most people may not realize that calcium is the ...

Eating vitamin D-rich foods can help improve calcium absorption in the gut and its deposition into bones. Prebiotics and probiotics may also help with calcium absorption by promoting healthy gut ...

Discover which makes your bones stronger as you age.

Calcium does more than strengthen bones; it supports muscles, nerves and mood. Discover the warning signs of deficiency and ...

Almost everyone knows calcium keeps bones and teeth strong. But here’s the thing: it does way more than just that. Calcium manages muscle movements, helps nerves work, controls your heartbeat, and ...