In 1963, on a hunch, a South African biologist named Sydney Brenner decided to study a species of worms named C. elegans. The worms turned out to be the perfect lab animal. They were simple creatures ...

C.elegans (Caenorhabditis elegans) is a free-living, transparent nematode (roundworm), about 1 mm in length, which naturally lives in temperate soil environments. C. elegans is a self-fertilizing ...

A new model for mechanical stress describes how growing organisms on a stiffer substrate can paradoxically worsen certain health outcomes while increasing lifespan, according to a USC Leonard Davis ...

Model organisms are vital to scientific research. They provide researchers with a way to analyze biochemical events in vivo and provide context for research. One such model is the roundworm ...

A new study on fatty acid acylation, or attachment, patterns onto proteins in Caenorhabditis elegans, a type of roundworm, provides a foundation for future discoveries around protein function and its ...

During animal cell division, a highly synchronized and tightly regulated dance of chromosomes takes place, ensuring the ...

C. elegans pictured in normal color conditions under a microscope. Credit: Jeremy Vicencio, Nadia Halidi/Centro de Regulación Genómica The researchers observed the same effects on health span, the ...

A workhorse of modern biology is sick, and scientists couldn't be happier. Researchers have found that the nematode C. elegans, a millimeter-long worm used extensively for decades to study many ...

A new protocol extends live imaging time for C. elegans larvae and adults using light sheet fluorescence microscopy from 20 minutes to more than 2 hours, while avoiding heat stress in the specimen.