Here are the Bills' toughest opponents in 2025. 5. Houston Texans This spot was a toss up between the Tampa Bay Buccaneers and the Texans.

The Chiefs will remain the AFC's toughest opponent in 2025, and as long as Andy Reid is still the head coach, they are the class of the conference. The secret to beating the Chiefs isn't a secret.

Buffalo Bills 2025 opponents Buffalo will have nine home games and eight away games in the 17-game regular season. In odd-numbered years, the AFC teams get an extra home game.

Here's a breakdown of the toughest games on North Carolina football's schedule in 2025, the Tar Heels' debut season under coach Bill Belichick.

If you rank the Bills’ schedule difficulty by the 2024 records of their upcoming opponents who last season had a 46.7% winning rate, the Bills’ 2025 schedule comes out 10th-easiest per that ...

RELATED: 4 toughest non-AFC East games on Bills' 2025 schedule As for the "easier" opponents, let's take a look at the three most winnable games on the schedule — outside of the AFC East.