Vitamin B12 is an essential vitamin, and low levels are linked to obesity. B12 shots could improve fatigue if you have a deficiency, but there’s not much research on them as a weight loss treatment.

This article was reviewed by Lynn Marie Morski, MD, JD. Key Takeaways: Tirzepatide with B12 is sometimes combined as a weekly injection for weight loss. Vitamin B12 supplementation may reduce fatigue ...

Medically reviewed by Kierra Brown, RD People with IBD are at higher risk of vitamin B12 deficiency due to inflammation and ...

Vitamin B12 helps your body turn food into energy, supporting your metabolism. People with obesity often have lower levels of vitamin B12. Low B12 levels can cause fatigue and brain fog, making it ...

Tirzepatide (Mounjaro®, Zepbound®) is a once-weekly diabetes and weight loss medication. Compounded tirzepatide is sometimes combined with vitamin B12 to provide additional health benefits. We’ll ...