Jacksonville Jaguars running back Bhayshul Tuten (33) is brought down in the second quarter by Los Angeles Chargers safety R.J. Mickens (27) in an NFL football game at EverBank Stadium, Sunday, November 16, 2025, in Jacksonville, Fla. [Doug Engle/Florida Times-Union] / Doug Engle/Florida Times-Union / USA TODAY NETWORK via Imagn Images

After a big win last week against the LA Chargers, the Jaguars improved to 6-4 on the season, and they are currently the seventh seed in the AFC playoff race. The Cardinals find themselves at 3-7 on the year and have won just one of their last eight games after a 2-0 start.

The Jacksonville Jaguars officially ruled out five players for Week 12, including OLB Travon Walker, LB Yasir Abdullah, OT Anton Harrison, TE Hunter Long, and WR Brian Thomas Jr.  It’s a tough break for their defense without one of their top edge rushers in Walker,

Jacksonville Jaguars rookie B.J. Green was informed he will be fined by the NFL for his vicious hit on Chargers QB Justin Herbert.

The Cardinals and Jaguars lock horns for the first time since 2021. Jacksonville hasn't visited Arizona since 2017. Here's what our T-U experts think.

The Jacksonville Jaguars will be without some important names when they take on the Arizona Cardinals in Week 12.

Jaguars tight end Brenton Strange will remain out for at least a couple more weeks after being placed on injured reserve on Oct. 7. Jacksonville misses the sure-handed tight end and could use help in the receiver room. Andrews helps on both ends, and his time is almost up in Baltimore (as is Baltimore's season).